Deseret Morning News, Saturday, November 05, 2005
U. makes a healing 'bio-paper'
By Lois M. Collins
Deseret Morning News
An emerging branch of medicine called "organ printing" takes a patient's own healthy cells and uses a printer, cell-based "bio-ink" and "bio-paper" to create tissue to repair a damaged organ.
Now a hydrogel or "bio-paper" developed by a University of Utah College of Pharmacy professor is a key component of a $5 million National Science Foundation-sponsored study that includes organ printing.
"Think of taking a blood vessel — a cylindrical object — and trying to reconstruct it in 3D with two-dimensional slices," said U. Presidential Professor of Medicinal Chemistry Glenn D. Prestwich, who created the hydrogel. He likens the resulting slices to a "non-nutritious doughnut" with muscle cells on the outside and endothelial cells inside. To make the cylinder, those flat doughnut sections are literally printed, one thin layer of cells and hydrogel at a time, the platform moving away from the printer's "bio-ink"-delivering needles as the cylinder grows.
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